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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
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PROTAC
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Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
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Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
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Pyrimidines
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Intermediates
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Ordering
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Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
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Services
Custom Synthesis
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Name Index S
Salicylanilide
(Catalog# : 16122766, Cas# :
87-17-2
)
Salicylanilides are a group of compounds with a wide range of biological activities i
Sivelestat (ONO-5046)
(Catalog# : 16122760, Cas# :
127373-66-4
)
Sivelestat is a potent and selective inhibitor of neutrophil elastase with IC50 of 44
Sivelestat sodium
(Catalog# : 16122758, Cas# :
201677-61-4
)
Sivelestat sodium is a competitive inhibitor of human neutrophil elastase, also inhib
SC75741
(Catalog# : 16122748, Cas# :
913822-46-5
)
SC75741 is a potent NF-B inhibitor with EC50 of 200 nM.SC75741 shows immunosuppressiv
SQ22536
(Catalog# : 16122726, Cas# :
17318-31-9
)
SQ22536 is an inhibitor of adenylyl cyclase with an IC50 of 1.4 M. It can inhibit PGE
SIS3
(Catalog# : 16122721, Cas# :
521984-48-5
)
SIS3, a novel specific inhibitor of Smad3, inhibits TGF- and activin signaling by sup
Saccharin 1-methylimidazole (SMI)
(Catalog# : 16122716, Cas# :
482333-74-4
)
SMI is considered a general-purpose activator for DNA and RNA synthesis.
STA-21
(Catalog# : 16122706, Cas# :
111540-00-2
)
STA-21 is a selective STAT3 inhibitor.In cells, STA-21 inhibits Stat3 DNA binding act
SKI II
(Catalog# : 6111526, Cas# :
312636-16-1
)
SKI-II is a synthetic inhibitor of sphingosine kinase (SK) activity with IC50 of 78 M
SR1001
(Catalog# : 6111522, Cas# :
1335106-03-0
)
SR1001 is a selective ROR and ROR inverse agonist; suppresses TH17 cell differentiati
S1P1 Agonist III
(Catalog# : 61119, Cas# :
1324003-64-6
)
S1P1 Agonist III is a potent and orally active S1P1 agonist with EC50 of 18 nM; no ac
SCH 546738
(Catalog# : 161113, Cas# :
906805-42-3
)
SCH 546738 is a novel, potent and non-competitive small molecule CXCR3 antagonist wit
4SC-202
(Catalog# : 611937, Cas# :
1186222-89-8
)
4SC-202 is an orally available potent HDACi specific for class I HDAC isoenzymes(NO H
SJB3-019A
(Catalog# : 611930, Cas# :
2070015-29-9
)
SJB3-019A is a potent and novel usp1 inhibitor. SJB3-019A (IC50 = 0.0781 uM) was 5 ti
SR-3029
(Catalog# : 611915, Cas# :
1454585-06-8
)
SR 3029 is a potent and highly specific CK1/CK1 inhibitor with the IC50 of 97 nM.SR-3
SB-216763
(Catalog# : 161009026, Cas# :
280744-09-4
)
SB-216763 is a glycogen synthase kinase-3 (GSK3) inhibitor, which can maintain mouse
SC79
(Catalog# : 161009025, Cas# :
305834-79-1
)
Akt Activator II, SC79, CAS 305834-79-1, is a cell-permeable compound that interacts
Sirolimus (Rapamycin)
(Catalog# : 161009003, Cas# :
53123-88-9
)
In cells, sirolimus binds to the immunophilin FK Binding Protein-12 (FKBP-12) to gene
Serlopitant(VPD-737)
(Catalog# : 16082501, Cas# :
860642-69-9
)
Serlopitant (VPD-737) is a drugwhich acts as an NK1 receptor antagonist. It was asses
SH-4-54
(Catalog# : 16071406, Cas# :
1456632-40-8
)
SH-4-54 is a potent STAT inhibitor with KD of 300 nM and 464 nM for STAT3 and STAT5,
Siponimod
(Catalog# : 16071404, Cas# :
1230487-00-9
)
Siponimod, also known as BAF-312, is a a potent and orally selective S1P Receptor Mod
SAR125844
(Catalog# : 16071023, Cas# :
1116743-46-4
)
SAR125844 is a potent and highly selective c-Met inhibitor with potential antineoplas
SRT2104
(Catalog# : 16071014, Cas# :
1093403-33-8
)
SRT2104, also known as GSK2245840, is a novel, first-in-class, highly selective small
Scriptid
(Catalog# : 16071007, Cas# :
287383-59-9
)
Scriptid
Sotrastaurin
(Catalog# : 16071004, Cas# :
425637-18-9
)
Sotrastaurin, also known as AEB-071, is an orally available pan-protein kinase C (PKC
SR-2211
(Catalog# : 16071002, Cas# :
1359164-11-6
)
SR-2211
SGX-523
(Catalog# : 16070912, Cas# :
1022150-57-7
)
SGX523 is a novel, ATP-competitive kinase inhibitor remarkable for its exquisite sele
SEA0400
(Catalog# : 16070911, Cas# :
223104-29-8
)
SEA0400 is a Na+/Ca2+ exchanger 1 inhibitor. SEA0400 prevents dopaminergic neurotoxic
SR 11302
(Catalog# : 16070908, Cas# :
160162-42-5
)
SR 11302
Sobetirome
(Catalog# : 16070907, Cas# :
211110-63-3
)
Sobetirome, also known as GC-1 and QRX-431, is a hyroid hormone beta-receptor agonist
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno
Adrixetinib ( Q-702 )
(Catalog# : 20617, Cas# :
2394874-66-7
)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag