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Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
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others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
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Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
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Custom Synthesis
Process Development
Ordering
Contact Us
About Us
Contact Us
+86-17702719238
sales@sun-shinechem.com
Home
Inhibitors&Agonists
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
Building Blocks
Aldehydes
Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
Catalysts
Chiral Compounds
Deuterated
Fluorides
Imidazoles
Indoles and Oxindoles
Iodos
Nitro Compounds
Oxazoles
Peg Linkers
Phenols
Piperidines
Pyridines
Pyrimidines
Quinolines
Sulfonamides
Thiazoles
Trifluoroborates
Other Azoles
Other Heterocycles
Other Building Blocks
On Sale
Intermediates
Services
Custom Synthesis
Process Development
Ordering
Contact Us
About Us
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Name Index S
Sonolisib
(Catalog# : 122944, Cas# :
502632-66-8
)
Sonolisib is a small-molecule wortmannin analogue inhibitor of the alpha, gamma, and
Soraphen A
(Catalog# : 122922, Cas# :
122547-72-2
)
Coming soon!
Sembragiline
(Catalog# : 122921, Cas# :
676479-06-4
)
Coming soon!
Saracatinib
(Catalog# : 122913, Cas# :
379231-04-6
)
Saracatinib is an orally available 5-, 7-substituted anilinoquinazoline with anti-inv
SU11274
(Catalog# : 122912, Cas# :
658084-23-2
)
SU11274 is a selective Met inhibitor with IC50 of 10 nM, no effects on PGDFR, EGFR or
STF31
(Catalog# : 122831, Cas# :
724741-75-7
)
STF31 is a potent glucose transporter 1 (GLUT1).
SM-164
(Catalog# : 122802, Cas# :
957135-43-2
)
SM-164 is a potent cell-permeable and bivalent Smac mimetic which bind to a XIAP prot
SB-742457 ( Intepirdine )
(Catalog# : 122518, Cas# :
607742-69-8
)
SB-742457(Intepirdine) is a highly selective 5-HT6 receptor antagonist with pKi of 9.
SNG-1153
(Catalog# : 122516)
Coming soon!
SGC0946
(Catalog# : 122504, Cas# :
1561178-17-3
)
SGC0946 is a highly potent and selective DOT1L methyltransferase inhibitor with IC50
(S)-2-Ethylpiperazine dihydrochloride
(Catalog# : 122503, Cas# :
128427-05-4
)
Coming soon!
SB-505124
(Catalog# : 122502, Cas# :
694433-59-5
)
SB-505124 is a selective inhibitor of TGFR for ALK4, ALK5 with IC50 of 129 nM and 47
SP-420
(Catalog# : 122304, Cas# :
1221411-72-8
)
SP-420 is an orally active small molecule that selectively binds iron and removes it
(3S)-3-aminooxolan-2-one,hydrochloride
(Catalog# : 120804, Cas# :
2185-03-7
)
Coming soon!
Salinosporamide A
(Catalog# : 111304, Cas# :
437742-34-2
)
Salinosporamide A is a novel marine derived proteasome inhibitor which inhibits CT-L,
Sitravatinib (MGCD516)
(Catalog# : 178906, Cas# :
1123837-84-2
)
Sitravatinib, also known as MGCD516 or MG516, is a novel small molecule inhibitor tar
SB-3CT
(Catalog# : 110220, Cas# :
292605-14-2
)
SB-3CT is a potent matrix metalloproteinase MMP-2 and MMP-9 inhibitor, which is a 2-[
Spautin-1
(Catalog# : 102622, Cas# :
1262888-28-7
)
Spautin-1 is a novel autophagy inhibitor, IM inhibited the growth of K562 cells with
STF-118804
(Catalog# : 102605, Cas# :
894187-61-2
)
STF-118804 is a highly specific NAMPT inhibitor; reduces the viability of most B-ALL
SB 525334
(Catalog# : 102205, Cas# :
356559-20-1
)
SB 525334 is a potent and selective inhibitor of TGF_beta_ receptor I (ALK5) with IC5
SAR191801
(Catalog# : 101917, Cas# :
1234708-04-3
)
Coming soon!
SEP-0372814
(Catalog# : 101913, Cas# :
1516895-53-6
)
Coming soon!
SP-2509
(Catalog# : 101909, Cas# :
1423715-09-6
)
SP-2509 is a novel histone demethylase LSD1 inhibitor, which showed high actitivity o
SB239063
(Catalog# : 101908, Cas# :
193551-21-2
)
SB 239063 is a potent p38MAPK inhibitor, which had an IC(50) of 44 nM for inhibition
SCR-1481B1
(Catalog# : 101901, Cas# :
1174161-69-3
)
SCR-1481B1 is a potent and selective MET inhibitor. SCR-1481B1 inhibited MET kinase w
SB-590885
(Catalog# : 101208, Cas# :
405554-55-4
)
SB590885 is a potent B-Raf inhibitor with Ki of 0.16 nM, 11-fold greater selectivity
SBC-115076
(Catalog# : 101002, Cas# :
489415-96-5
)
SBC-115076 is an anti-proprotein convertase subtilisin kexin type 9 (anti-PCSK9) comp
Selonsertib(GS-4997)
(Catalog# : 100503, Cas# :
1448428-04-3
)
Selonsertib is a apoptosis signal-regulating kinase inhibitor (ASK1). Selonsertib may
SAG
(Catalog# : 92802, Cas# :
912545-86-9
)
SAG is a potent Smoothened (Smo) receptor agonist (Kd = 59 nM); antagonizes Cyclopami
(1S,3r,5R)-8-(5,6,7,8-tetrahydro-6-(5-isopropyl-2-methylphenyl)-2-(3,5-dimethyl-1H-indazol-4-yl)
(Catalog# : 91813, Cas# :
1421249-72-0
)
Coming soon!
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Products Catalog
Signaling Pathway
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
Inhibitors & Agonists
Intermediates
Building Blocks
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
New Products
Natural Compounds
Latest Products
HC-5404
(Catalog# : 24112, Cas# :
3034479-99-4
)
HC-5404 is a novel, highly selective and potent PERK inhibitor.
STX-478
(Catalog# : 20633, Cas# :
2883540-92-7
)
STX-478 is a second generation, mutant-selective, oral PI3Ka small molecule allosteri
Iclepertin (BI-425809)
(Catalog# : 24084, Cas# :
1421936-85-7
)
Iclepertin (BI-425809) is an oral, small-molecule inhibitor of GlyT-1for the treatmen
Bomedemstat
(Catalog# : 24001, Cas# :
1990504-34-1
)
Bomedemstat is anorally available, irreversible inhibitor of lysine-specific demethyl
PLX-4545
(Catalog# : 24111, Cas# :
2892065-45-9
)
PLX-4545 is an orally bioavailable molecular glue degrader of IKZF2 designed to desta
VVD-130037 ( BAY-3605349 )
(Catalog# : 24110, Cas# :
3034880-93-5
)
VVD-130037 (BAY-3605349) is an oral, small-molecule activator of KEAP1 (INrf2).
CBR-5884
(Catalog# : 24109, Cas# :
681159-27-3
)
CBR 5884 is a phosphoglycerate dehydrogenase (PHGDH) inhibitor which was able to inhi
JHU-083
(Catalog# : 24108, Cas# :
1998725-11-3
)
JHU-083 selectively blocks glutaminase activity in brain CD11b+ cells and prevents de
LXH-3-71
(Catalog# : 24107, Cas# :
2251753-65-6
)
LXH-3-71 isnovel "molecular glue"that induces the interaction between PHGDH
CC-92480 ( Mezigdomide )
(Catalog# : 20510, Cas# :
2259648-80-9
)
CC-92480 Is a Novel Cereblon E3 Ligase Modulator with Enhanced Tumoricidal and Immuno