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+86-17702719238
sales@sun-shinechem.com
首页
抑制剂/受体激动剂
PI3K/Akt/mTOR
Epigenetics
Protein Tyrosine Kinase
Angiogenesis
Apoptosis
Autophagy
JAK/STAT
MAPK
Cytoskeletal Signaling
Cell Cycle
TGF-beta/Smad
DNA Damage
Stem Cells & Wnt
Ubiquitin
Neuronal Signaling
NF-κB
GPCR & G Protein
Metabolism
Anti-infection
Proteases
Immunology & Inflammation
Vitamin D Related
Membrane Transporter/Ion Channel
others
PROTAC
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Amines
Amino Acids
Anilines
Boronic Acids
Bromides
Carboxes
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Chiral Compounds
Deuterated
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Pyridines
Pyrimidines
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Other Azoles
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Cas号索引 1
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Cas号索引 1
1228780-72-0 | 1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine
(Catalog# : 61110004)
1-{[2-(4-chlorophenyl)-4,4-dimethylcyclohex-1-en-1-yl]methyl}piperazine
1319207-44-7 | CC0651
(Catalog# : 611933)
CC0651 is an allosteric inhibitor of the human cdc34 ubiquitin-conjugating enzyme tha
1421693-22-2 | CDKI-73
(Catalog# : 611920)
CDKI-73 is a potent CDK9 inhibitor with Ki of 4 nM; shows selective toxicity to CLL c
1391855-95-0 | CDK9-IN-6
(Catalog# : 611919)
CDK9-IN-6 is a CDK9 inhibitor, refers to Example 399 in WO 2012101062 A1
1402821-24-2 | Ca2+ channel agonist 1
(Catalog# : 611918)
Ca2+ channel agonist 1 is a N-type Ca2+ channel activity agonist, with EC50 of 14.23
1309357-15-0 | CX-4945 sodium salt
(Catalog# : 611912)
CX-4945 (Silmitasertib) sodium salt is a potent and selective ATP-competitive small m
1431697-78-7 | CAL-130 Hydrochloride
(Catalog# : 611823)
CAL-130 Hcl is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported tha
1431697-74-3 | CAL-130
(Catalog# : 611822)
CAL-130 is a novel phosphoinositide 3-kinase (PI3K) inhibitor. It is reported that co
168425-64-7 | Compound 401
(Catalog# : 611816)
Compound 401 is a synthetic inhibitor of DNA-PK (IC50 = 0.28 M) that also targets mTO
1300118-55-1 | CC-115 hydrochloride
(Catalog# : 611815)
CC-115 hydrochloride is a inhibitor of mTOR/DNA-PK (IC50= 21/ 13 nM). CC-115 shows go
1218777-13-9 | CAY10505
(Catalog# : 160926016)
CAY10505 is a phosphatidylinositol 3-kinase- inhibitor , was found to significantly i
1007207-67-1 | CH5132799 (PA-799)
(Catalog# : 160926015)
CH5132799, also known as PA-799, is a novel class I PI3K inhibitor, which exhibited a
1489389-18-5 | CCT245737
(Catalog# : 16090101)
CCT245737(CCT-245737, CAS 1489389-18-5) is the first orally active, clinical developm
1564286-55-0 | CWHM-12
(Catalog# : 16071407)
vitro ligand-binding assays, with somewhat less potency against v5 than against the o
1032568-63-0 | Copanlisib
(Catalog# : 16070917)
Copanlisib, also known as BAY 80-6946, is a phosphoinositide 3-kinase (PI3K) inhibito
1404095-34-6 | CCT244747
(Catalog# : 16070913)
CCT244747 is a novel potent, highly selective, orally active ATP-competitive CHK1 inh
134448-10-5 | CA-074
(Catalog# : 16062115)
CA-074
163042-96-4 | CF-102
(Catalog# : 16053104)
CF-102, also known as 2-Cl-IB-MECA, is an orally bioavailable, synthetic, highly sele
156177-65-0 | CEP-1347
(Catalog# : 032402)
Coming soon!
1446144-04-2 | CPI-203
(Catalog# : 030201)
CPI 203 is a novel potent, selective and cell permeable inhibitor of the bromodomain
194423-06-8 | CL-387785
(Catalog# : 022202)
CL-387785 is an irreversible inhibitor of EGFR with IC50 of 370+/-120 pM; is able to
1228013-30-6 | CC-223
(Catalog# : 021802)
CC-223 is a potent mTOR kinase inhibitor (IC50=16 nM), with >150-fold sensitivity
1228013-15-7 | CC-115
(Catalog# : 012004)
CC-115 is a dual inhibitor of DNA-dependent protein kinase and mammalian target of ra
1542705-92-9 | CB-5083
(Catalog# : 012002)
CB-5083 is a novel first in class, potent orally bio-available p97 inhibitor that dis
1056636-06-6 | CYT387 sulfate salt
(Catalog# : 011916)
CYT387 sulfate is an ATP-competitive inhibitor of JAK1/JAK2 with IC50 of 11 nM/18 nM,
1051375-10-0 | Cabotegravir
(Catalog# : 011816)
Cabotegravir is a potent HIV integrase inhibitor as an oral lead-in tablet and long-a
184025-19-2 | Ciproxifan maleate
(Catalog# : 010420)
Ciproxifan maleate is a highly potent and selective histamin H3-receptor antagonist w
1338806-73-7 | CFI-400945
(Catalog# : 123012)
CFI-400945 is an orally available fumarate salt form of CFI-400945, a polo-like kinas
1339928-25-4 | CUDC-907
(Catalog# : 12309)
CUDC-907 potently inhibits class I PI3Ks as well as classes I and II HDAC enzymes.
176957-55-4 | CCT007093
(Catalog# : 122839)
CCT 007093 is an effective PPM1D inhibitor that selectively reduces viability of huma
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产品分类
信号通路
-- PI3K/Akt/mTOR
----
PI3K
----
Akt
----
GSK-3
----
S6 Kinase
----
AMPK
----
DNA-PK
----
MELK
----
PIKfyve
----
PI4K
----
PTEN
----
mTOR
----
ATM
----
PDK-1
----
ATR
-- Epigenetics
----
PARP
----
JAK
----
Pim
----
PKC
----
PKD
----
Sirtuin
----
Histone Demethylase
----
Histone Acetyltransferase
----
HDAC
----
HIF-PH
----
Aurora Kinase
----
Histone Methyltransferase
----
METTL3
----
Epigenetic Reader Domain
-- Protein Tyrosine Kinase
----
VEGFR
----
EGFR
----
PDGFR
----
IGF-1R
----
FLT3
----
FGFR
----
c-Kit
----
Src
----
ALK
----
Ephrin receptor
----
BTK
----
Trk receptor
----
c-Met/HGFR
----
Syk (Spleen tyrosine kinase)
----
TAM Receptor
----
ULK1
----
CSF-1R
----
TYK2
----
ROS Kinase
-- Angiogenesis
----
VEGFR
----
JAK
----
EGFR
----
PDGFR
----
FLT3
----
FGFR
----
Bcr-Abl
----
Src
----
ALK
----
Syk
----
FAK
----
BTK
----
HIF
-- Apoptosis
----
PD-1
----
PD-L1
----
Bcl-2
----
Caspase
----
TNF-alpha
----
Survivin
----
IAP
----
PERK
----
p53
----
Mdm2
----
E1/E2/E3 Enzyme
-- Autophagy
----
LRRK2
----
CXCR
----
Autophagy
-- JAK/STAT
----
JAK
----
STAT
----
Pim
----
EGFR
-- MAPK
----
MEK
----
Raf
----
p38 MAPK
----
ERK
----
MNK
----
Mixed Lineage Kinase
----
JNK
----
MAP4K
-- Cytoskeletal Signaling
----
Akt
----
Bcr-Abl
----
PKC
----
FAK
----
HSP
----
Kinesin
----
Integrin
----
Dynamin
----
Wnt
----
β-catenin
-- Cell Cycle
----
CDK
----
PD-1
----
PD-L1
----
Chk
----
ROCK
----
PLK
----
APC
----
Wee1
----
DYRK
----
c-Myc
----
Aurora Kinase
----
ROCK inhibitor
-- TGF-beta/Smad
----
Bcr-Abl
----
PKC
----
ROCK
----
TGF-beta/Smad
-- DNA Damage
----
PARP
----
DNA/RNA Synthesis
----
Sirtuin
----
Topoisomerase
----
DNA-PK
----
Telomerase
----
RAD51
----
HDAC
----
ATM
----
DNA alkylator
----
Mps1
-- Stem Cells & Wnt
----
GSK-3
----
JAK
----
STAT
----
ROCK
----
TGF-beta/Smad
----
Wnt
----
γ-secretase
----
β-catenin
----
smo
-- Ubiquitin
----
Proteasome
----
p97
----
Deubiquitinase
-- Neuronal Signaling
----
COX
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
GABA Receptor
----
OX Receptor
----
Amyloid-β
----
5-HT Receptor
----
γ-secretase
----
Adrenergic Receptor
----
NMDA Receptor
----
GlyT1
----
Beta-secretase
----
α-Synuclein
----
Tau Protein
----
Cannabinoid Receptor
----
Transthyretin (TTR)
-- NF-κB
----
NF-κB
----
HDAC
----
IKK
-- GPCR & G Protein
----
Histamine Receptor
----
Dopamine Receptor
----
Opioid Receptor
----
Endothelin Receptor
----
SGLT
----
OX Receptor
----
CaSR
----
CXCR
----
Vasopressin Receptor
----
Glucagon Receptor
----
Prostaglandin Receptor
----
5-HT Receptor
----
Adrenergic Receptor
----
Cannabinoid Receptor
----
Sphingosine 1 Phosphate Receptor
----
PKA
----
Adenosine Receptor
----
GnRH
----
LPL Receptor
----
Sigma Receptor
----
Ras
----
mAChR
----
Cholecystokinin Receptor
----
Melanocortin Receptor
----
RXFP Receptor
-- Metabolism
----
PPAR
----
P450
----
HSP
----
PDE
----
Factor Xa
----
Phospholipase
----
FAAH
----
CETP
----
Lipoxygenase
----
HMG-CoA Reductase
----
Fatty Acid Synthase
----
FXR
----
NAMPT
----
TDO
----
Carbonic Anhydrase
----
Monoamine Oxidase
----
IDO
----
MAGL
----
Epoxide Hydrolase
----
LXR
----
Myeloperoxidase (MPO)
----
RAR/RXR
----
Acyltransferase
----
UGT
----
MMP
----
ATP Citrate Lyase
-- Anti-infection
----
CMV
----
Filovirus
----
HBV
----
HCV
----
HIV
----
HSV
----
Influenza Virus
----
RSV
----
SARS-CoV
----
Antibacterial
----
Antifungal
----
Parasite
-- Proteases
----
Proteasome
----
Caspase
----
HIV Protease
----
MMP
----
γ-secretase
----
DPP4
----
Mitochondrial Metabolism
----
Isocitrate Dehydrogenase (IDH)
----
FPTase
----
Acetyl-CoA Carboxylase
----
Glutaminase
-- Immunology & Inflammation
----
PD-1
----
PD-L1
----
COX
----
CCR
----
Histamine Receptor
----
TLR
----
CXCR
----
MALT
----
TDO
----
NOS
----
NADPH-oxidase
----
IDO
----
Thrombopoietin Receptor(TPO)
----
NLR inhibitor
----
Interleukin Related
----
CD73
----
Complement System
----
Aryl Hydrocarbon Receptor
-- Vitamin D Related
----
VD/VDR
-- Membrane Transporter/Ion Channel
----
BCRP
----
CFTR
----
EAAT2
----
GABA Receptor
----
HCN Channel
----
Monoamine Transporter
----
Na+/Ca2+ Exchanger
----
Na+/K+ ATPase
----
nAChR
----
Calcium Channel
----
Chloride Channel
----
CRAC Channel
----
GlyT1
----
iGluR
----
P2X Receptor
----
P-glycoprotein
----
Amino acid transporter
----
Monocarboxylate Transporter
----
Potassium Channel
-- others
----
PKK
----
Others modulator
----
Estrogen Receptor/ERR
----
ChoKα
-- PROTAC
----
Molecular Glues
抑制剂/受体激动剂
中间体
分子砌块
--
Aldehydes
--
Amines
--
Amino Acids
--
Anilines
--
Boronic Acids
--
Bromides
--
Carboxes
--
Catalysts
--
Chiral Compounds
--
Deuterated
--
Fluorides
--
Imidazoles
--
Indoles and Oxindoles
--
Iodos
--
Nitro Compounds
--
Oxazoles
--
Peg Linkers
--
Phenols
--
Piperidines
--
Pyridines
--
Pyrimidines
--
Quinolines
--
Sulfonamides
--
Thiazoles
--
Trifluoroborates
--
Other Azoles
--
Other Heterocycles
--
Other Building Blocks
--
On Sale
新产品
天然化合物
最新产品
2883540-92-7 | STX-478
(Catalog# : 20633)
STX-478 是第二代突变体选择性口服 PI3Ka 小分子变构抑制剂。
1421936-85-7 | Iclepertin (BI-425809)
(Catalog# : 24084)
Iclepertin(BI-425809)是一种口服的GlyT-1小分子抑制剂,用于治疗与
1990504-34-1 | Bomedemstat
(Catalog# : 24001)
Bomedemstat 是一种口服的、不可逆的赖氨酸特异性去甲基酶 1 (LSD1)
2892065-45-9 | PLX-4545
(Catalog# : 24111)
PLX-4545 是一种口服生物可利用的 IKZF2 分子胶降解剂,旨在破坏高
3034880-93-5 | VVD-130037 ( BAY-3605349 )
(Catalog# : 24110)
VVD-130037 (BAY-3605349) 是一种口服小分子 KEAP1 (INrf2) 激活剂。
681159-27-3 | CBR-5884
(Catalog# : 24109)
CBR 5884 是一种磷酸甘油酸脱氢酶 (PHGDH) 抑制剂,能够抑制过度表达
1998725-11-3 | JHU-083
(Catalog# : 24108)
JHU-083 选择性阻断大脑 CD11b+ 细胞中的谷氨酰胺酶活性,并防止慢
2251753-65-6 | LXH-3-71
(Catalog# : 24107)
LXH-3-71是一种新型“分子胶”,可诱导PHGDH和DDB1-CUL4泛素连接酶之
2259648-80-9 | CC-92480 ( Mezigdomide )
(Catalog# : 20510)
CC-92480 是一种有效的新型 CELMoD 化合物,旨在快速最大程度地降解
2394874-66-7 | Adrixetinib ( Q-702 )
(Catalog# : 20617)
Adrixetinib is a tyrosine kinase inhibitor with potential use as an antineoplastic ag